Chapter 3 Resequencing studies

This is a technical review for resequencing studies.

3.1 Technical review

3.1.1 Simulation

Bifurcating genealogy using Hudson’s coalescent theory (for a mini review please see Richard Hudson and Norman Kaplan on the Coalescent Process, \(Genetics\), 2016, 202, 865-6)

Kelleher, Etheridge, and Mcvean, Efficient Coalescent Simulation and Genealogical Analysis for Large Sample Sizes, \(PLoS Computational Biology\), 2016, 12:e1004842

3.1.2 NGS

3.1.3 Chip data

3.1.4 GBS

3.2 Drop HWE test